Laboratory of Enteric Bacteriology
Activities of microbiological
surveillance and research
Typhoid fever
- Application
of ELISA, PHA (Passive Haemagglutination), rapid test (using serum and urine
specimens) in research on typhoid fever.
- Research
on production of diagnostic reagents for public health centers at provincial
level: Vi sensitized sheep red blood cell, culture
media.
- Follow
up of the carrier status in patients after treatment and in their contacts
(by stool culture).
- Examination
of Vi antigen concentration by ELISA and PHA in the investigation of carrier
of Salmonella Typhi.
- Examination
of drug resistance of Salmonella Typhi:
Disk diffusion assay (technique of Kirby-Bauer), MIC and antibiotic resistance
by molecular mechanism.
Diarrhea
- Surveillance on the important infectious diarrhoeal pathogens: Vibrio cholerae, Salmonella spp., Shigella spp., E.coli…
- Study on molecular epidemiology
of Vibrio cholerae.
- Study on the role of Kappa-phage (vibriophage)
and application in prediction of cholera epidemic
- Study on rapid test for the diagnosis
of dysentery.
- Study on opportunistic diarrhoeal
pathogens in immunodeficiency people (HIV-infected subjects, malnutrition children,
aged people…): Cryptosporidium, Microsporidia,
Cyclospora, Isospora, Blastocystis, E.coli…
- Study on virulent and toxin genes
of E.coli pathogens: EPEC, ETEC,
EHEC, EIEC, DAEC, EAggEc
- Study on antibiotics susceptibility
and resistant mechanism of diarrhoeal bacteria.
Food-borne infections
- Detection of bacterial pathogens in foods and specimens
of cases with food poisoning
- Detection of LT, ST genes of E.coli isolated from foods and cases
with food poisoning.
Checking and confirmation
of isolated strains
- Determination
of the antimicrobial activity of the medication, the extracts from plants,
antimicrobial products…
- Isolation,
detection and confirmation of the pathogens from clinical specimens
Prevention and
control of biological agents (for biological war)
Determination of Bacillus anthracis.