Hoang Thuy Long, Nguyen Thu Van, Do Tuan Dat, Hoang Quynh Tran, Nguyen Van Cuong,
Nguyen Thanh Hao1, David Hipgrave, Vu Minh Huong2, Dinh Van Hai, Nguyen Dang Ngoan3.
1National
2
Project "Strengthening Immunization and Malaria Control in
3
Health Service and
1581 persons from two different geometry areas of Thanh Hoa
provine; Quang Xuong plane district and Ngoc Lac middle-lane district, had
participated in the Serosurvey of Hepatitis B and C virus (HBV and HCV) in
August 1998. All had divided into 4 age groups representative as different
modes of viral transmission; 2 Infant groups: 9-18 months old and 4-6 years old
, Adolescent group - 14-16 years old and Adult group - 25-40 years old. Nearly
half of objects sampling had exposed to HBV, the rate of HBcAb positive
increases upon ages and up to 81.4% of Adults. The rate of HBsAg carriers is
17% and no significant difference between age groups. More than 85% of Infant
HBsAg carriers are HBeAg positive, this rate of Adolescent
and Adult is lower (71.1% and 30.4% respectively) - Therefore HBV infection of
Infant easely becomes chronic carrier state. HBsAb increases upon ages and only
3.4% of Infant 9-18 months old has this antibody. Only 6 samples (0.38%) and no
one of Infant are positive among 1563 anti-HCV tests. Conclusively, Thanh Hoa
is low prevalence of HCV infection and high prevalence, similarly the common rate
of HBV infection in